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Source: http://video.today.msnbc.msn.com/today/50807676/
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Friday, February 15, 2013
Vision restored with total darkness in kittens with amblyopia
Feb. 14, 2013 ? Restoring vision might sometimes be as simple as turning out the lights. That's according to a study reported on February 14 in Current Biology, a Cell Press publication, in which researchers examined kittens with a visual impairment known as amblyopia before and after they spent 10 days in complete darkness.
Researchers Kevin Duffy and Donald Mitchell of Dalhousie University in Canada believe that exposure to darkness causes some parts of the visual system to revert to an early stage in development, when there is greater flexibility.
"There may be ways to increase brain plasticity and recover from disorders such as amblyopia without drug intervention," Duffy says. "Immersion in total darkness seems to reset the visual brain to enable remarkable recovery."
Amblyopia affects about four percent of the general population and is thought to develop when the two eyes do not see equally well in early life, as the connections from the eyes to visual areas in the brain are still being refined. Left untreated, that imbalance of vision can lead to permanent vision loss.
In the new study, the researchers examined kittens with amblyopia induced by experimentally depriving them of visual input to one eye. After those animals were plunged into darkness, their vision made a profound and rapid recovery. Further examination suggested that the restoration of vision depends on the loss of neurofilaments that hold the visual system in place. With those stabilizing elements gone, the visual system becomes free to correct itself.
Darkness therapy holds promise for the treatment of children with amblyopia, the researchers say, but don't try this at home. They think that the darkness must be absolute to work, with no stray light at any time. It is also important to address the original cause of the amblyopia first, and to ensure that a period of darkness will not harm an individual's good eye.
The researchers are still working out just how much darkness is required, and for how long. Regardless, they say it is unlikely that a drug could ever adequately mimic the effects of darkness that they've seen.
"The advantage of a simple nonpharmacological sensory manipulation, such as a period of darkness, is that it may initiate changes in a constellation of molecules in a beneficial temporal order and in appropriate brain regions," they write.
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The above story is reprinted from materials provided by Cell Press, via EurekAlert!, a service of AAAS.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Kevin R. Duffy, Donald E. Mitchell. Darkness Alters Maturation of Visual Cortex and Promotes Fast Recovery from Monocular Deprivation. Current Biology, 14 February 2013 DOI: 10.1016/j.cub.2013.01.017
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/g1Um5nZadnE/130214133916.htm
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MetLife Signs on as Global Sponsor of 2013 World Baseball Classic
NEW YORK--()--MetLife has signed on to be a Global Sponsor and the Official Insurance Company of the 2013 World Baseball Classic. MetLife, and its brand ambassador Snoopy, will be incorporated into multiple aspects of the event including in-stadium exposure and on worldwide media platforms. MetLife, a leading global insurer operating in 46 countries worldwide, is joining Brand USA, Delta Air Lines and Konami as the fourth Global Sponsor of the tournament.
?With MetLife?s strong presence in Japan and Korea where the sport is widely popular, and with market leading positions in countries like Mexico and the U.S., millions of our customers and thousands of our employees are looking forward to watching some of the world?s best play baseball this March.?
As part of the agreement, MetLife will be the title sponsor of the All-World Baseball Classic Team. The MetLife All-World Baseball Classic Team will be comprised of the best performers at each position during the tournament. Players selected to the previous two teams have included two-time tournament M.V.P. Daisuke Matsuzaka (Pitcher, Japan ? 2006 and 2009), Ken Griffey Jr. (Outfielder, USA ? 2006), Adrian Beltre (Third baseman, Dominican Republic ? 2006) and Hyun-Soo Kim (DH, Korea ? 2009).
MetLife?s long experience and expertise in covering premier sporting events from above will allow it to provide dynamic aerial coverage from its blimps ? Snoopy One, Snoopy Two and Snoopy J. The MetLife blimps will be flying above all the games played in Phoenix, Arizona; Miami, Florida; Tokyo, Japan and in San Francisco, California. A camera will be in each blimp capturing scenic aerial footage, as well as crucial in-game moments, that will be incorporated into the game broadcasts on MLB Network, ESPN Deportes and the worldwide feed being distributed to more than 200 countries and territories.
To add to the excitement and fan experience at the games, Snoopy, donning a World Baseball Classic jersey, will be making special appearances, interacting with fans and distributing gifts.
"With such a strong presence in the global marketplace, MetLife is well-positioned to illuminate its brand message across the expansive World Baseball Classic platform," said Paul Archey, Senior Vice President, International Business Operations, Major League Baseball. "MetLife will have a variety of touch points, both inside and outside the tournament venues, fully integrating them into the event program this March."
"It?s an honor to welcome MetLife to the World Baseball Classic?s roster of Global Sponsors," said Timothy Slavin, member of the World Baseball Classic Board of Directors. "The World Baseball Classic looks forward to working with MetLife, Snoopy and the entire Peanuts gang to help shine a spotlight on the world?s greatest players competing for national pride and global bragging rights. We?re confident MetLife?s global brand awareness will be enhanced and strengthened by its association with the world?s premier international baseball tournament."
"Many of the countries fielding World Baseball Classic teams are also countries where MetLife is a leading insurer," said Richard Hong, vice president of brand, advertising & promotion, MetLife. "With MetLife?s strong presence in Japan and Korea where the sport is widely popular, and with market leading positions in countries like Mexico and the U.S., millions of our customers and thousands of our employees are looking forward to watching some of the world?s best play baseball this March."
The 2013 World Baseball Classic, which is the third edition of the tournament, will feature the world?s best players representing their countries and territories. Thirty-nine games will be played in seven venues in four nations and territories from March 2 through March 19, 2013. Team Japan is the two-time defending champion of the World Baseball Classic, having won in 2006 and 2009. The World Baseball Classic, which is officially sanctioned by the International Baseball Federation (IBAF), will for the first time in 2013 be recognized as the official national team World Championship, with the winner being crowned the 2013 World Baseball Classic Champion and the IBAF World Champion.
For the first time, four Qualifiers were held for the 2013 World Baseball Classic, which expanded the competitive field from 16 to 28 countries. Brazil, Canada, Chinese Taipei and Spain emerged from the Qualifiers to earn spots in the March 2013 event. Those four Qualifier teams will join the teams of the 12 countries/territories ? Australia, China, Cuba, Dominican Republic, Italy, Japan, Korea, Mexico, Kingdom of the Netherlands, Puerto Rico, United States and Venezuela ? that received automatic invitations based on their performances in the 2009 tournament.
In the United States, MLB Network will be the exclusive English-language broadcast partner for all 39 games while ESPN Deportes will be the Spanish-language partner. The Semi-Final and Final games will take place from March 17-19 at San Francisco?s AT&T Park, hosted by the San Francisco Giants. Second round games will be held in the Tokyo Dome in Tokyo, Japan from March 8-12 and at Marlins Park in Miami, Florida from March 12-16. First round games will be held at the Fukuoka Yahoo! Japan Dome in Fukuoka, Japan from March 2-6; at Intercontinental Stadium from March 2-5 in Taichung, Taiwan; at Hiram Bithorn Stadium in San Juan, Puerto Rico from March 7-10; and at Chase Field and Salt River Fields at Talking Stick in Phoenix, Arizona from March 7-10.
About the World Baseball Classic
The World Baseball Classic is the premier international baseball tournament, sanctioned by the International Baseball Federation, and features the best players in the world competing for their home countries and territories. More than 1.5 million fans from all over the world have attended the tournament games, held in March 2006 and 2009. Team Japan is the reigning World Baseball Classic Champion, taking home both the inaugural and 2009 titles. The upcoming World Baseball Classic will be played in March 2013 and will again feature the greatest baseball-playing nations in the world. The tournament will be held every four years thereafter.
About World Baseball Classic, Inc.
World Baseball Classic, Inc. (WBCI) is a company created at the direction of Major League Baseball (MLB) and the Major League Baseball Players Association (MLBPA) to operate the World Baseball Classic tournament. The tournament, which is sanctioned by the International Baseball Federation (IBAF), is supported by MLB, the MLBPA, Nippon Professional Baseball (NPB), the Korea Baseball Organization (KBO), their respective players associations and other leagues and players from around the world.
About the International Baseball Federation
The International Baseball Federation (IBAF) is the world governing body for baseball, comprising 122 national member federations. Together with its member federations, the IBAF is dedicated to the promotion, development, and organization of baseball around the world. The IBAF is the sole entity recognized by the International Olympic Committee for overseeing and sanctioning all national team competition. The IBAF headquarters are located in Lausanne, Switzerland.
About MetLife
MetLife, Inc. is a leading global provider of insurance, annuities and employee benefit programs, serving 90 million customers. Through its subsidiaries and affiliates, MetLife holds leading market positions in the United States, Japan, Latin America, Asia, Europe, the Middle East and Africa. Metropolitan Life Insurance Company, New York, NY 10166.
Source: http://feeds.businesswire.com/click.phdo?i=61cd73c286fd70356dc9c3cd32386725
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The Engadget Podcast is live tonight at 5PM!
Do you feel that? Love is in the air, here at the Engadget Lovecast. And it's the purest love of all -- the love between bloggers and gadget news. Join us in the chat, after the break. We've got plenty of love to give.
Source: http://www.engadget.com/2013/02/14/the-engadget-podcast-is-live-tonight-at-5pm/
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New Image: EW.com reveals new ?Breaking Dawn, Part 1? nightmare wedding behind the scenes photo
EW.com revealed this new image of Kristen Stewart and Robert Pattinson on the set waiting to film the Bella?s nightmare version of Bella Swan and Edward Cullen?s wedding ceremony from ?The Twilight Saga: Breaking Dawn, Part 1.? ??The Twilight Saga: Breaking Dawn, Part 2? and ?The Twilight Saga: Breaking Dawn, Part 1, Extended Edition? are arriving on Blu-ray, DVD and VOD on March 2. 
About the author: Amy Taylor View all posts by Amy Taylor
Amy is a lifelong fangirl, who gets most excited over The Twilight Saga, Harry Potter, Disney, Star Trek, superhero movies, and Broadway musicals. She?s Twilight fan fiction writer, Esme Mom Cullen, and her work is (mostly) focused on her favorite ship ? Carlisle and Esme. She has the sarcasm and wit of a born and raised Jersey Girl, even though she now makes her home in Southern California, She currently works in the areas of communications and corporate social responsibility.
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Friday, February 1, 2013
Port Orchard, WA 2008 Chrysler 300 Used Sedan Bremerton, WA Gig Harbor, WA Bruce Titus Port Orchard Ford for $19,999
- Champagne
- DKD96893A
- 3.5L V6
- 2C3LA33G08H237393
- Automatic 4 Speed
- 35,051 mi.
- RWD Sedan (4 Door)
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Interior
- Leather seats
- Rear bench seats
- Heated drivers seat
- Heated passenger seat
- Front seat type - Bucket
- 8-way power adjustable drivers seat
- 8-way power adjustable passenger seat
- Climate controlled - Driver and passenger heated-cushion, driver and passenger heated-seatback
Convenience
- Compass
- Tachometer
- Trip computer
- Cruise control
- Power steering
- Clock - Analog
- Power heated mirrors
- Remote power door locks
- Adjustable pedals - Power
- Universal remote transmitter
- External temperature display
- Power windows with 2 one-touch
- Audio controls on steering wheel
- Tilt and telescopic steering wheel
- Overhead console - Mini with storage
- Multi-function remote - Trunk/hatch/door
- Air conditioning with dual zone climate control
Technical
- 4 Doors
- Rear-wheel drive
- 250 hp horsepower
- Automatic Transmission
- 3.5 liter V6 SOHC engine
- Fuel economy EPA highway (mpg): 24 and EPA city (mpg): 17
Safety
- Passenger Airbag
- Stability control
- 4-wheel ABS brakes
- Dusk sensing headlights
- Front fog/driving lights
- Traction control - ABS and driveline
Exterior
- Privacy/tinted glass
- Intermittent window wipers
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Payment $315.58 |
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*The advertised price does not include sales tax, vehicle registration fees, finance charges, documentation charges, and any other fees required by law. We attempt to update this inventory on a regular basis. However, there can be lag time between the sale of a vehicle and the update of the inventory.
EPA mileage estimates are for newly manufactured vehicles only. Your actual mileage will vary depending on how you drive and maintain your vehicle.
Before purchasing this vehicle, it is your responsibility to address any and all differences between information on this website and the actual vehicle specifications and/or any warranties offered prior to the sale of this vehicle. Vehicle data on this website is compiled from publicly available sources believed by the publisher to be reliable. Vehicle data is subject to change without notice. The publisher assumes no responsibility for errors and/or omissions in this data the compilation of this data and makes no representations express or implied to any actual or prospective purchaser of the vehicle as to the condition of the vehicle, vehicle specifications, ownership, vehicle history, equipment/accessories, price or warranties. 2008 Chrysler Seattle, WA 2008 Chrysler Tacoma, WA 2008 Chrysler Olympia, WA
Source: http://www.brucetitus.com/2008-Chrysler-300-Port-Orchard-WA/vd/13343428
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Wawa Hits One Million Facebook Fans
Wawa hit one million Facebook fans on Jan. 28, and has launched a two week celebration to reward fans for their loyalty.
From merchandise to gift cards, Wawa is showering its social media fans with affection. But the celebration doesn?t end there; Wawa is also launching its ?What Will Wawa do Next?? program.
?Through the years, Wawa fans have posted thousands of requests and wishes, so in honor of our Millionth Fan Celebration, some of those requests will be fulfilled,? said Carol Jensen, Wawa?s chief marketing officer. ?This program is just one way Wawa is showing appreciation for the wonderful fans that have made this milestone possible.?
Fans can enter the contests and view the details by visiting Wawa?s Facebook page for entry forms and details.
Fun Facebook Facts
To put the milestone in perspective, consider the following Wawa Facebook Fun Facts:
?? Out of Facebook?s more than 42 million Fan Pages, Wawa ranks 5,520 in terms of Likes ?standing strong in the top 99%.
??Wawa is the 848th ranked brand overall and the 234th brand in the Food/Beverage category.
?? Wawa is one of only approximately 5,000 Fan Pages that have reached the one million fan milestone.
?? Wawa?s fans have used Facebook to interact MORE than 550,000 times since the page launched, including likes, comments, shares, and answers.
?? If you live in the Mid?Atlantic market and you?re not a fan of Wawa on Facebook, at least one of your friends is!
?We treasure this brand loyalty and unique way to interact with our fans and customers,? said Jensen. ?Our Millionth Fan Celebration is just one way of thanking our wonderful fans for their unwavering support of Wawa by adding some fun elements of surprise and delight to them!?
Wawa also experienced 384% growth on its Twitter page since June. For more on other chains doing a great job with social media, and how you can boost your social media presence, check out CSD?s social media awards: http://www.csdecisions-digital.com/csdecisions/201301#pg53
Source: http://www.csdecisions.com/2013/01/30/wawa-hits-one-million-facebook-fans/
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